Thursday, 30 April 2020

ANC - 1

13th Part

Q   Describe the objectives, target group, and the services provided under the following national nutrition programs:
(c)  National Prophylaxis Programme for Prevention of Nutritional Blindness  6  
A   Objectives: The main objective of the program is to prevent blindness due to vitamin A deficiency in children (between 6 months to 5 years) by supplying a mega (high) dose of vitamin A.
Target group: All children of 6 months to 5 years are eligible (particularly those living in rural, tribal, and urban slum areas).

Dose and distribution strategy: A liquid preparation of vitamin A in oil giving 200,000 IU (in 2 ml) is given to every child between the ages of 1 and 5 years. Vitamin A solution is kept away from direct sunlight and a bottle once opened is utilized within 6-8 weeks. A child must receive a total of 9 oral doses of vitamin A by the fifth birthday. An infant between the age of 6-11 months is given a dose of 100,000 IU. The contact with an infant is established during the administration of the measles vaccine between the age of 9-12 months. It is considered a practical time for administering the vitamin A supplement of 100,000 IU to infants. Distribution of vitamin A is carried out by the Auxiliary Nurse Midwife (ANM) - a functionary belonging to the Health Department in the Ministry of Health and Family Welfare

Q  Describe the objectives, target group, and the services provided under the following national nutrition programs:
(a) National Nutritional Anaemia Control Programme                    7
A  Objectives: The main aim of the program is to significantly decrease the cases of anaemia among women in the reproductive age group especially pregnant and lactating women and preschool children. The program focuses on the following :
# Promotion of regular consumption of foods rich in iron.
# To provide iron and folate supplements in the form of tablets to the "high risk" groups.
# Identification and treatment of severely anaemic cases.

Target group: The beneficiaries of the program are :
a) Pregnant women
b) Lactating mothers
c) Family planning acceptors (women who accept family planning measures like tubectomy)
d) Children of both-sexes between ages 1 to 5 years.

Distribution Strategy: Supply of iron-folic acid tablets to the target population. Two types of tablets being distributed are :
(1) big tablets, each containing 60 mg of iron (ferrous sulphate) & 500 Ug of folic acid (for women). One big tablet per day for 100 days should be given to a pregnant women after the first trimester. Similarly, lactating women and IUD acceptors should receive one tablet per day for 100 days. Mothers often accompany their infants on immunization sessions. They can be handed over tablets during this time.
(2) small tablets, each containing 20mg of iron and 100Ug of Folic acid for children daily for 100 days every year. For young children who cannot swallow tablets, iron and folk acid in 2 ml of syrupy liquid (in the same dose, as in a small tablet) should be given. Auxiliary Nurse Midwife (ANM) a functionary belonging to the Health Department in Ministry of Health and Family Welfare is responsible for the distribution of the tablets.

Q  What is the basis of the National Prophylaxis Programme for Prevention of Nutritional Blindness?
A  The basis of the program is the fact that the human liver can store large amounts of vitamin A. If large doses of vitamin A are given to preschool children, they can be stored and used whenever needed.

Q  State whether the following statements are true or false. Correct the false statements.
a)  Women of childbearing age and children are the target beneficiaries of the National Anaemia Control Programmes.
A  True
b)  Nutritional anaemia can be only due to iron and folic acid deficiency.
A  False; It can also be due to vitamin B12 deficiency
c)  Anaemia can even lead to the death of women during childbirth.
A  True
d)  Sixty milligrams of iron is given to women during pregnancy as a prophylactic measure.
A  True
e)  The dosage of iron and folic acid in the National Nutritional Anaemia Control Programme is the same for women and children.
A  No, Children are given smaller doses.

Q  Besides goitre other manifestations of iodine deficiency disorders include.................. and ................…
A    hypothyroidism, speech & hearing defects, muscular weakness, spasticity, stillbirth.

Q  National goitre control program was launched in the year ................ and is now known as ......................…
A  1962,  Iodine prophylaxis program

Q  Ten grams of iodized salt provides.. ..................... .micro, grams of iodine.
A  150
Q  Common salt is fortified with ..................... a compound of iodine.
A  potassium iodate

Q  List the main objectives of the Iodine Prophylaxis Programme.
A  The main objectives of the National IDD Control Programme are-
- to identify regions where IDD(goitre,cretinism) is rampant
- to supply iodized salt in endemic areas
- to assess the impact of the program over a period of time

Q  Why is salt chosen as the vehicle of supplying iodine in our country?
A  The main reasons are given below :
i) Salt is consumed by all communities of the country
ii) The consumption of salt is almost the same in all communities with minor variations.
iii) It is produced at few selected locations and hence its quality can be easily Monitored.
iv) The addition of iodine doesn’t change the appearance or taste.  
v) The technology to add iodine is not complicated or expensive.   

Q  Growth monitoring
Q  What is growth monitoring? Why is it useful to assess the nutritional status of children? 2+4
A  Growth Monitoring is a regular assessment of physical growth and measurement of the child through different ways (weight, length) which enables mothers to visualize growth or lack of it. Relevant and practical guidance thereafter can be obtained to ensure continued regular growth and health of children.
       The purpose of Growth Monitoring is to help identify the at-risk child, take action on the first sign of inadequate growth and integrate nutrition intervention (breastfeeding, supplementary feeding, etc.) with other health interventions (Immunization, ORT) to restore health and proper growth of children. Growth Monitoring is a preventive and promotive strategy aimed at the action before malnutrition occurs. 

Q  Complementary feeding practices
A.  Supplementary feeding means giving extra food to make up for the lack of energy and protein in a diet in order to prevent nutritional deficiencies among children. It is done by slowly substituting breast milk with solid and semi-solid foods. Breastfeeding is continued but the baby slowly gets accustomed to other foods along with breast milk so as to overcome the shortfall in the nutrients. This process of introducing foods other than breast milk in the diet of the infant is called supplementary feeding.
     In general, based on the age of the infant supplementary foods vary as follows:
(a) Liquid Supplements at - (4- 6 months)- it includes juices, soups or other milk substitutes (like animal milk)
(b) Semisolid to solid supplements(6 - 8 months) -well cooked and mashed, soft thin, liquid porridge made from the staple food of the community. The porridge can be prepared by cooking the cereals (i.e. wheat, rice, semolina, etc.) with milk and sugar.
(c) solid supplements( 8-12 months) - chopped vegetables like potato and carrots boiled and cut into small pieces. Minced meat and boiled fish could be served as such instead of mashing. Soft cooked rice or small pieces of chapaties may also be introduced at this stage.

6. a) Explain the principle of food preservation involved in the following: (1+1)
i.  Wax coating of Jam
A.  Certain micro-organisms require air for growth (aerobes) that ultimately leads to spoilage of food. Wax coating prevents air from coming in contact with the jam thus stopping the growth of aerobes. Hence by wax coating, we prevent jams from spoiling.

ii.  Blanching of vegetables before freezing.
A.  Natural enzymes lead to decay of vegetables. Blanching is a process in which we boil or steam vegetables briefly until they are partially cooked.  Blanching of vegetables before freezing destroys natural enzymes present in them and hence prevents self decomposition of food.

Q  List the different methods used for the assessment of nutritional status. Give the significance of anthropometric measurements in assessing nutritional status  (4)
A.  There are four major methods used to assess the nutritional status of individuals these are -
1. Anthropometric method - The anthropometric method refers to the measurements of body size. The four most commonly used body measurements which serve as good indicators of nutritional status are :
#  Weight for the age - Weight for age is a commonly used indicator of body size. It reflects the level of food intake. The relative change of weight with age is a more sensitive indicator of short duration malnutrition.

#  Height for age - Length or height is a very reliable measure. It reflects the total increase in the size of the individual up to the moment it is determined. For example, we know that normally a baby measures 50 cm at birth. This birth length increased to 75 cm at one year of age. By the age of four years, the child is 100 cm tall. Thereafter, the child gains about 5 cm in height every year, until the age of 10 years. Recording the height helps us to know whether the child is growing normally and if the health of the child is good or not.

#  Mid upper- Arm circumference for the age - The mid-upper arm circumference is an indicator of nutritional status of individuals and communities. Arm circumference normally increases with age, but between one to five years it does not change much and remains fairly constant. At this time the baby fat is replaced by muscle. Measuring the arm circumference of this age group helps us to know whether the child is in good health or not. The MUAC is, therefore, an easy and useful method of assessing the nutritional status of children in the age group 1-5 years. One can measure the roundness/fatness of a child's arm, using any ordinary measuring tape by placing it around the middle part of the child's left arm and recording the value. A measurement of less than 12.5 cm indicates severe malnutrition and a measure between 12.5 cm and 13.5 cm indicates moderate malnutrition.

#  Weight for height - Weight for height is a very good index for short duration malnutrition. This measurement is of value especially in situations where child health services are not available. Periodic monitoring is not available children are seen irregularly say once in a while.

2. Clinical method - Clinical examination is one of the simplest methods to assess nutritional status. It involves looking for changes (clinical signs/symptoms) in the body which are indicative of a particular deficiency. For example, bitot spots and night blindness in children suggest the possibility of vitamin A deficiency, paleness, lethargy in women suggest the possibility of anaemia.

3. Biochemical analysis - In this method, the body fluids (blood and urine normally) are analyzed to determine the nutritional status of individuals. For example. the level of Hb in the blood gives us an indication of iron content(or lack of it) in the body, a measure of the level of thiamine in the urine reflects the intake of thiamine in the diet, a measure of the level of vitamin A in the blood reflects intake and reserve of vitamin A in the body.

4. Diet survey - A systematic inquiry into the food supplies and food consumption of individuals and population groups is called diet survey. Dietary data can be collected covering a whole nation from families (of different economic classes) or from individuals of special age group or occupation depending on the need. There is a wide range of methods used in diet surveys like food frequency, diet history, 24-hour recall method, food record or diary, etc. The main purpose of the diet survey is -
# to collect information about food supplies and food consumption of individuals
and population groups.
# to find out inadequacies in the existing diet pattern.
{ The 24-hour recall: The 24-hour recall method is probably the most widely used method of dietary assessment. Under this method, the subject/individual is asked to Recall/describe, in as much detail as possible the food intake for the past 24 hours.
The individual recalls what was eaten, how much food was eaten, how was the food prepared, when was it eaten and other such details related to food intake.)

Significance of anthropometric measurements -  Anthropometric measures refer to the measurements of body size. Growth, as measured in terms of weight for age or height for age, reflects the sum total of what has occurred up to that point in time. Besides height and weight, measuring body circumference facilitates the identification of the degree of body fat and the number of lean body tissues i.e. muscles in the body. It aids in the identification of PEM and obesity.  

i.  Vitamin C plays an important role in wound healing
A.  Vitamin C plays an important role in wound healing because of the formation of a special kind of protein called collagen. The formation of collagen at the site of wound or injury aids in its healing. This protein is found in the connective tissue which holds together different other tissues much like cement holds bricks together. For example, collagen present in blood vessels makes them firm. The deficiency of vitamin C in the diet may result in fragile blood vessels which can easily rupture.

iv.  Colostrum is beneficial for infants
A.  Before milk is secreted colostrum is produced by the breast. Colostrum should be fed to the baby as it is good for growth and general well being. Colostrum is life-saving as it has protective functions. It contains a high concentration of antibodies and white blood cells which protects the child from infections.

iv)  Amylase rich food
A.  Amylase rich food is the flour obtained from germinated grain. Germinated grain flour contains a lot of amylases an enzyme that makes the porridge soft thin and easy to eat without taking away any of its nutritive value.

v)  Synergism    
A.  The interaction between two diseases resulting in increased complications or increased duration of the disease is called synergism. For example, if a child with moderate PEM also has infections like measles or diarrhoea, then due to synergism between these two diseases he may develop a severe form of kwashiorkor.

i)  Essential and non-essential amino acids
A.  Proteins are built up of just 22 amino acids. Of these, about 8 cannot be manufactured by the body while the rest can be manufactured. Those which cannot be manufactured by the body must be supplied by the diet. These amino acids are called essential amino acids. The amino acids which can be manufactured by the body are called non-essential amino acids.                                             
Essential Amino acids - Leucine, Lysine, Valine.
Non-Essential Amino acids - Cystine, Glycine, Proline.

iv)  Food laws and food standards
A.  Food laws - Food laws are extremely important for providing wholesome, nutritious, poison-free food to the public. Food laws encourage the production and handling of food under hygienic conditions and also prevent the chemical and microbiological contamination which are responsible for the outbreak of food-borne diseases and other health hazards affecting large segments of the population.
Food standards - It is considered as a specification or set of specifications that are to be met. Quality characteristics include those relating to general appearance, size, and shape, gloss, color, consistency, etc. We have two organizations that are empowered to lay down standards of quality for food items and to certify that these standards are met. These are the Bureau of Indian Standards (BIS) and the Directorate of Marketing and Inspection.

v)  IDDM and NIDDM
A.  Insulin-dependent diabetes mellitus (IDDM) - In this type of diabetes mellitus (in order to function normally) body is dependent on insulin doses from an exogenous source (outside source). It occurs more frequently in young children and adolescents.
Non-Insulin dependent diabetes mellitus (NIDDM) - In this type of diabetes mellitus there is a lack or insufficiency of insulin in the body which can be brought under control by either diet alone or a combination of diet and certain drugs. The body is not dependent on insulin from an outside source. This is frequently observed in adults (especially those who are overweight).

4.  Fill in the blanks
i) In dehydration, there is a loss of fluids and …………
A. Electrolytes

ii)  Bodyweight is less than ……..Kg is a risk factor during pregnancy
A. 8 Kg

iii)  The toxins present in Kesari dal affect the ………..system
A.  Nervous system

iv)  In the case of lactation failure …………milk is suitable for the babies.
A.  Cow milk

v) …………….present in green leafy vegetables and cereals interfere with absorption of calcium/phosphorus.
A.  (Phytates in cereals and) Oxalates in green leafy vegetables.

3.  List the deficiency and food sources of the following nutrients/substances: (5)
i) Thiamine
ii) Niacin
iii) Iodine
iv) Vitamin B12
v) Riboflavin
A. I) Thiamine or BI - is widely distributed in animal and plant foods. Plant foods such as whole-grain cereals (i.e. wheat and rice) and whole pulses are also rich sources of thiamine. Among the foods of animal origin lean meats, poultry, and egg yolk are good sources.
             Thiamine is a part of coenzymes that play a role in the metabolism of carbohydrates. Deficiency of thiamine in the diet can, therefore, interfere with carbohydrate metabolism.

Ii)  Niacin - Niacin is another member of the B-complex family. The good sources of niacin include meat, fish, poultry, cereals, pulses, nuts, and oilseeds. One interesting point about niacin is that it can also be formed in the body from an amino acid called tryptophan which is available in milk.
         Niacin (like riboflavin) is also part of coenzymes that help to release energy from the end products of the digestion of carbohydrates, fats, and proteins. It thus helps in their metabolism. The deficiency of Niacin could create problems in the digestion of carbohydrates, fats, and proteins.

Iii) Iodine - Crops such as vegetables especially those grown in coastal areas where iodine content of the soil is high have substantial amounts of iodine. Seafood like fish, shellfish are among the best sources of iodine.
             Iodine is a component of the hormone thyroxine secreted by the thyroid gland. Thyroxine regulates the rate of oxidation within the cells. If this regulation does not take place, both physical and mental growth will be affected. Iodine helps in the functioning of nerve and muscle tissues. The deficiency of iodine could lead to a disease called goitre.

Iv)  Vitamin B12 -  Vitamin B 12 or cobalamin is present only in the foods of animal origin. Liver, kidney, milk, eggs, and seafood (e.g. shrimps, crabs, lobsters) are rich sources of vitamin B 12.
         Vitamin Biz is necessary for the proper functioning of the digestive tract, nervous system, and bone marrow. In the bone marrow, vitamin B12 (like folic acid) is also involved in the formation of normal red blood cells. The deficiency of Vitamin B12 is thus extremely harmful to the proper functioning of the body.

v) Riboflavin - Riboflavin or B2 is widely distributed in plant and animal foods. Milk, liver, kidney, eggs, and green leafy vegetables are good sources of riboflavin. Whole grain cereals and pulses contain fair amounts.
          Riboflavin plays an important role in the metabolism of carbohydrates, fats, and proteins. This is because of the fact that it forms part of two distinct co-enzymes which help to release energy from the end products of digestion of carbohydrates, fats, and proteins. Its deficiency would lead to reduced metabolism of carbohydrates, fats, and proteins. 

ANC - 1

12th Part

Q  Ariboflavinosis  (SN)  5
Q List the clinical features and measures you would adopt to prevent the following disorders: 5
(a) Ariboflavinosis
A  Ariboflavinosis (Riboflavin deficiency)
This is a nutritional deficiency which occurs due to reduced intakes of riboflavin through the diet. Riboflavin deficiency is one of the most common among Vitamin B-complex deficiencies. It is common among poor people where diets contain negligible amounts of pulses and milk. Meat is consumed, but very rarely. As a result, riboflavin deficiency is very common in our country among the poor population.

Clinical Features: The major clinical features of ariboflavinosis include:-
a) Angular Stomatitis: One of the clinical signs of ariboflavinosis is angular stomatitis. The subjects develop cracks on both the sides (angles of upper and lower lips) of the mouth. This is a very common sign noticed among children. As high as 30-35% of the children exhibit angular stomatitis. Since it doesn’t cause much discomfort children and the adults ignore it.   
b) Glossitis: This is particularly common among women, especially during pregnancy. The tongue becomes raw and red. There will be a burning sensation whenever foods that are hot and rich in spices are consumed. The tip of the tongue is affected first. In severe deficiency, the tongue may develop cracks as well.
c) Cheilosis: The lips develop cracks and become red.  
Preventive measures -
Milk is a good source of riboflavin. We have to make sure that the communities include foods rich in riboflavin like green leafy vegetables, whole cereals, and pulses, and cheaper nuts in their everyday diet to prevent ariboflavinosis.  

Q  Clinical features of pellagra    (SN)    5
A  Pellagra (Niacin deficiency)
This is a nutritional deficiency which occurs due to reduced intakes of niacin, one of the B-complex group vitamins in the diet. Though it is not as common as ariboflavinosis, pellagra is more frequently seen in the Telengana & adjoining parts of Maharashtra and Karnataka.
Clinical features: Pellagra is characterized by typical skin changes, diarrhoea, and mental changes. The patients suffering from pellagra exhibit typical skin changes. These changes are symmetrical and are evident only on the parts of the body that are exposed to the sun like forearms and legs, face, and the exposed parts of the neck. The skin becomes dry and scaly.
Diarrhoea i.e. loose motions is also present among some patients. Patients of pellagra have slight mental changes. These include irritability, forgetfulness, and loss of orientation. There may be headaches and sleeplessness, tremors of hands and legs, and mental depression. Mental changes may be very noticeable when the patient suffers from severe niacin deficiency.
Prevention - We should encourage the communities to consume which are rich in niacin like mixed cereal diets, pulses, Milk, Nuts, oilseeds, and organ meats are also good sources.  

Q  Beri-Berl     5
Q  Clinical features of Beriberi   4
A  Beriberi (Thiamine deficiency)
Beriberi is a nutritional deficiency disease caused by the deficiency of the vitamin thiamine in the diet. This disease is rare in our country.
Clinical features - The individual experiences loss of appetite, weakness, and heaviness in the legs. The person also becomes tired easily.
The patient complains of the feeling of pins and needles and numbness in the legs.
There may be loss of sensation i.e. loss of the feeling of touch over the legs. The disease occurs in two forms as wet beriberi or dry beriberi. In the case of wet beriberi, there is an accumulation of fluid in the body. This can ultimately lead to heart failure.
       In the case of dry beriberi, the patient will feel a weakness in the legs, if the disease advances the patient becomes completely bedridden.  
Causes: The disease is due to the inadequacy of thiamine in the diet. The disease is very common in communities where polished rice is consumed frequently. This is due to the fact that polishing the thin outer layer of rice (which contains thiamine) is removed.   
Prevention - Prevention: Consumption of paraboiled rice or hand pounded rice is the best source of thiamine. An increase in the consumption of pulses and other thiamine-containing foods like yeast and whole wheat flour and millets prevents beri-beri.  

Q  Describe the clinical features of Vitamin D deficiency in children       5
Q  Osteomalacia         2
Q  Enumerate the clinical features and measures for the control of Rickets
A  Rickets is a disease that occurs due to the deficiency of vitamin D among growing children in which the bones become soft and deformed. Osteomalacia is the adult form of vitamin D deficiency.
Clinical features -
Rickets - In the initial stages of the disease, children become restless, muscles lose their firmness and become flabby. The abdominal muscles also lose their firmness. Due to Rickets, teeth erupt late in children. The children suffering from rickets take more time than normal children to sit and crawl. In some cases, the child is too weak and is unable to walk.
      Due to this disorder, there are deformities seen in the bones. Deformities of the chest with the breast bone are common. This symptom is called pigeon chest. Some children may have "bow legs" (bent like a bow) or "knock knees when both the knees will be touching each other, unlike in normal children. Deformities of the backbone also may develop if the disease continues beyond the age of 2 years.
Prevention: Adequate exposure to sunlight is the most important factor in protecting the child from rickets. Dietary sources are few and the vitamin is found chiefly in fish liver oils and egg yolk.  

OSTEOMALACIA -
Osteomalacia is the adult form of the deficiency of Vitamin D. Osteomalacia is common among women of reproductive age (15-45 years of age). This is more common among women who have had multiple (many) pregnancies. The disease is frequently seen among women belonging to low socio-economic groups depending on poor diets and who are confined to the house.
Clinical features: Pain in ribs, hip bone, lower back, and legs is the most common complaint. There are muscular weakness and the woman suffering from disease usually finds it difficult to climb stairs. There will be pain on the application of pressure on the bones like the hipbone. Sometimes there may be fractures of the bones. Deformities of the backbone are common.   

Prevention - Vitamin D supplements are given to suspected patients like pregnant women who are generally confined indoors and in women who had multiple pregnancies.   

Q  Enumerate the clinical features and measures for the control of Scurvy. 8
A  Scurvy is a nutritional deficiency disorder that occurs due to a deficiency of vitamin C in the diet. It is observed among people who don’t consume fresh fruits and vegetables in their diet for a very long time period.

Clinical features: The most important clinical sign of scurvy is spongy, bleeding gums. The gums are swollen, particularly in the region between the teeth. They bleed even on slight touch. The infection of gums is also very common.

Causes: Scurvy is due to the consumption of diets that do not contain fresh fruits and vegetables for very long periods. This leads to a deficiency of vitamin C or ascorbic acid.

Prevention: Amla, guava, citrus fruits (lime, orange), are rich sources of vitamin C. Amla is, in fact, the richest source of vitamin C. Similarly sprouted (germinated) pulses like whole Bengal gram are good sources of vitamin C. Communities should be educated to include one of these foods in the diet regularly.       

Q  Differentiate between dental and skeletal fluorosis.     4
Q  Describe the causes and clinical features of Fluorosis                 6
A  Fluorosis is a disease which is caused due to consumption of excessive amounts of the mineral fluorine for a very long time period. Fluorosis is an important health problem in some districts in the States of Andhra Pradesh, Punjab, Karnataka, Tamil Nadu, and Rajasthan.

Causes: The main source of fluoride for human consumption in India is drinking water. Drinking water should contain less than 1 mg per liter of fluoride. In areas where fluorosis is common, the fluoride content of water is as high as 3-12 mg/liter.  
Clinical features: Fluorosis can be seen as changes that take place in the teeth (dental fluorosis) and in bones (skeletal fluorosis).
Dental Fluorosis: Among children who are living in areas where fluorosis is common, the disease affects the teeth. The teeth lose their shine and chalky, white patches appear on them. This is known as mottling of teeth. Mottling is considered as an early sign of fluorosis. Later, these white patches become yellowish. In severe cases of fluorosis, the enamel gets eroded ultimately leading to depressions on the teeth. This is known as pitting.
Skeletal Fluorosis: In older individuals, fluorosis leads to changes in the bones because of the consumption of excess quantity of fluoride for prolonged periods. Initially, the individual will have pain in the neck and stiffness of the back. As the disease progresses it will lead to difficulty in the movement of the neck and back. We can see the changes in bones when X-rays are taken of patients suffering from skeletal fluorosis. In severe cases of skeletal fluorosis the patient will be completely bed-ridden.   
Prevention: Fluorosis can be prevented hut cannot be cured. The best method to prevent fluorosis is to consume water that has less than 1 mg per litre of fluoride. In other words, steps should be taken to supply drinking water with safe levels of fluoride to the communities to prevent fluorosis. Where this is not possible defluoridation (removal of excess fluorine) of water is the only alternative.   

Q  Describe the causes and clinical features of Lathyrism.      6
A  Larhyrism is a disease of the nervous system which is caused by the consumption of a pulse, kesari dal for a prolonged period.
Causes: Kesari dal (Lathyrus sativus) contains a toxin that affects the nervous system (neurotoxin). The toxin causes damage to the nervous system. This disease is common among landless agricultural labourers in Madhya Pradesh, Bihar, and Uttar Pradesh. In fact, kesari dal is a hardy crop that can survive even in severe droughts when much of the wheat crop is damaged. Particularly during drought seasons, the agricultural laborers depend solely on kesari dal. The agricultural labourers in these areas receive the dal from the landlords as wages. They prepare rotis using the dal and consume the same.  

Clinical features: This is a disease of the nervous system. In the initial stages, the individual exhibits a gait (walking style) which looks awkward. At this stage, if the dal is withdrawn further progress of the disease can be controlled.  
In the first stage, the patient will walk with jerky movements without the aid of a stick. This is called the no-stick stage. As the disease progresses, the patient can walk only with the support of a stick. This is called the one stick stage. During this stage, the patient walks on his toes with the support of a stick with the knees slightly bent. While walking, there is the crossing of legs, one over the other.
When the symptoms are more severe, the patient can walk only with the support of
Two sticks (two stick stage). The gait is slow and clumsy. The legs cross one over the other while walking and the knees are markedly bent. The patient gets tired very easily while walking even for short distances. Ultimately the knees are bent completely and the patient can only crawl. This is called the crawling stage. Young agricultural labourers are affected by the disease.   

Prevention - Banning of the crop is the surest way of preventing the disease. In fact, under the Prevention of Food Adulteration Act of Government of India, kesari dal is banned in all forms i.e. whole dal and flour. Unfortunately, it is not being effectively operated in States like Madhya Pradesh and Bihar where the problem of lathyrism is common.   

Q  Explain the dietary management of Diarrhoea, Measles   6+6
A  Diarrhoea -
The dietary considerations include :
I)  Advice the mothers to continue breastfeeding especially if the child is breastfed or alternatively gives milk feeds mixed with an equal amount of boiled, clean water.
2)  Serve soft, well-mashed, non-spicy foods to the child which are easy to digest. For example, soft well-cooked rice with dal preparation or khichri, soups, eggs, fish, etc. can be given to the child.
3)  Give the child foods rich in potassium such as fruit juices, mashed bananas, potatoes, carrots, well-cooked whole grain cereals.
4)  Give the child food as much as he wants and at least 5-7 times a day.
5)  As soon as diarrhoea starts, give the child more fluids than usual for example, rice water(kanjee), fruit juice, coconut water, buttermilk (lassi), dal soup, diluted milk, tea, nimbu'pani (fresh lime m water), barley water or any other fluid available at home and acceptable to the child.
6)  Give oral rehydration solution (ORS) to the child. ORS is a solution made from sugar and salt dissolved in water. This solution helps in regaining of the fluids and electrolytes that lost in the stools due to diarrhoea.

Measles -
Dietary considerations to be advocated are: -
a)  If the child is breastfed, advise the mother to continue breastfeeding the baby.
b)  Give to the child liquids like milk or semi-solid preparations like Kanjee, soft khichri; nutritious potridges which have been thinned by the addition of ARF.
{ARF is nothing but a few grams of germinated wheat powder which has the ability to instantly break down the thickness of gruels and to make them much easier for a sick child to swallow.}
c)  If the child also has diarrhoea, the mother should be advised to give the child oral rehydration solution to prevent dehydration.  
d)  All children with measles should get a large dose of vitamin A (200,000 IU.) orally by mouth.
e)  Ensure proper feeding of the child suffering from measles. If the child is properly fed  the reduction in body weight will be much less.

Q  Oral Rehydration Therapy   5
A  ORS is a solution made from sugar and salt dissolved in water. Take one liter of clean water (preferably boiled and cooled), add three-finger pinch of common salt and four-finger scoop of sugar, and mix well. This mixture is as good as the electrolyte mixtures available in the market. It is now known that salt (as stated above) added to one litre of thin rice kanjee or barley water will also serve as well. The child should be fed this solution as frequently as possible and after every loose stool.   

Q  Explain the effect of malnutrition on the infection.      5
A  a)- Reduction in antibody production: Due to the consumption of the right kind of nutrients in sufficient amounts, normal children have disease-fighting substances called antibodies that prevent infections and in case he does get infected, he recovers fast from infections. Moreover, the ill effects of the infections are also negligible in the normal child. However, in the case of severe PEM, or vitamin A deficiency there is a reduction in antibody production thereby, making the child more prone to infections.  
b) Effect on skin and mucous membrane: Among the normal fed children, the skin, mucous membranes, and other tissues are healthy and they prevent the entry of infectious agents in the body. These tissues act as barriers and prevent the entry of bacteria and germs from entering the human body. In children suffering from malnutrition (PEM), such a protective mechanism is absent. The secretion of mucous may be reduced and the mucous membrane becomes permeable. Consequently, a malnourished child can catch infections easily.  
c) PEM and worm infestation:- Proper mobility (movement) of the digestive tract is important for normal digestion. In individuals with malnutrition this mobility of the digestive tract slows down, as a result of it, there is more time available for the worms to multiply. In such individuals worm infections like roundworm disease may become severe. In addition, gastrointestinal infections may also become severe in malnourished individuals.  

ANC - 1

11th Part

Q  Prevention of PEM in a community  ( short notes)     5
A  Some of the measures are -
1  Prevention of PEM should start with the mother of the child. The main reason for low birth weight is maternal malnutrition i.e. the mother of the child consumes inadequate quantities of energy and protein during her pregnancy. Therefore, one must ensure that a pregnant woman consumes extra food to meet the additional needs of pregnancy.
2  Mother's milk is the best food for an infant. Lactating mothers should be encouraged to breastfeed their children as long as possible. By the age of about 6 months, however, the mother's milk alone is not adequate for the child. Supplementary food should be provided to the children by the age of six months, in addition to breast milk.
3  Children should be fed 5-6 times a day. As Indian diets are quite bulky and unless the child is fed frequently it cannot meet the energy and protein requirements.  
4  Infections like diarrhoea and respiratory infections increase the risk of PEM. Prompt treatment of these infections is necessary to help to prevent PEM. In addition, during diarrhoea and any other infection, food should not be restricted. The child should be fed as usual.      
5  Protection of children against diseases like tuberculosis or measles, whooping cough by immunization is another important aspect in the prevention of PEM.  

Q  Discuss the main causative factors of protein-energy malnutrition in children. 5
Q  Causative factors of PEM 7
A  Some of the causes of PEM are :
a) Poverty: PEM occurs in poor Indian communities. It is commonly seen in families of landless agricultural labor, and tribal communities without any regular earnings among others. In India, PEM is seen in backward communities of Harijans, nomadic tribes, and children in urban slums. These communities are poor, illiterate, and generally have large families.
b) Maternal malnutrition: The nutritional status of the mother determines the state of nutrition of the child to be born. The main reason for low birth weight is maternal malnutrition i.e. the mother of the child consumes inadequate quantities of energy and protein during her pregnancy.
c)  Infections and poor hygiene:  Infections like diarrhoea and respiratory infections increase the risk of PEM. The mothers may follow unsound and unhygienic methods of feeding the child. Feeding bottles may not be properly sterilized. Flies may be allowed to sit on the nipple of the feeding bottle. This may lead to frequent diarrhoea and lead to marasmus.
d)  Ignorance: Both the forms of PEM occur as a result of ignorance of the mother, in addition to poverty. The mother, due to ignorance;.delays the introduction of supplementary food (in addition to breast milk), even up to the age of 1 year. This has serious consequences because mother's milk alone is not enough for the child by the age of 6 months. The infant should be given supplementary foods in addition to breast milk. Moreover, the mothers restrict the diet when the child is suffering from infections such as diarrhoea, measles, and common fevers. This practice is not good since such a dietary restriction leads to PEM in children who are underfed.
e)  Wrong child feeding practices: The child is usually given the same diet as taken by the adults. The typical Indian diet is based on cereals and is quite bulky for a small child. This would mean that the child can consume only smaller amounts of food at one time. As a result, the child does not get adequate food. Consequently, the child cannot get enough energy, protein which is the major cause of PEM in India.

Q  PEM (Define)                               5
A  PEM can be defined as a range of pathological conditions arising from the deficiency of protein and energy and is commonly associated with infections. Protein-energy malnutrition (PEM) is widely prevalent among young children (0-6 years), however, it is also observed among adolescents and adults, mostly lactating women, especially during periods of famine or other emergencies. PEM has serious consequences for the health of individuals particularly children and can even result in death.  
Clinical features of PEM -
PEM is a condition characterized by two forms:
a) Marasmus
b) Kwashiorkor
The symptoms of are Marasmus - very low body weight for age, loss of fat (fat under the skin), gross muscle wasting. It is observed more frequently in infants and very young children.
Kwashiorkor, on the other hand, is a condition characterized by oedema (excessive accumulation of fluid in the intercellular spaces of tissue) and very low body weight for age. The syndrome is most frequently observed in children aged 1-3 and is precipitated by an infection or by a series of infections.

Enumerate the clinical features and measures for the control of the following disorders :
(a) PEM                                                        5
A  Marasmus -
 (How to identify a child suffering from Marasmus?)
Some common clinical features of marasmus include :
i) Muscle Wasting: The characteristic sign of marasmus is the extensive wasting of muscle with little or no fat under the skin. The ribs are clearly visible. Because of the absence of fat, the skin starts dangling with a number of folds, particularly on the buttocks. The child with marasmus, thus, can be described as a combination of skin and bones.

ii) Failure to thrive: The child suffering from marasmus usually is irritable and fretful. In fact, the child is often so weak that the cry of the child cannot even be heard.
iii) Growth failure: Failure to grow is another important feature of the disease. The children often weigh about 50 percent or less of normal children for their age. For example, a healthy normal one-year-old child weighs about 10 kg, whereas, a marasmic child would weigh only about 5 to 6 kg.
Iv) Deficiency& Infections - The child may also suffer from frequent watery diarrhoea associated with dehydration (loss of fluids). The child may also have other deficiencies particularly, vitamin A deficiency.   

Kwashiorkor 
(How to identify a child suffering from Kwashiorkor?)
Some common clinical features of Kwashiorkor include:
i) Oedema: Oedema is the excessive accumulation of fluid in the intercellular spaces of the tissues. Oedema is usually observed on the lower limbs, but it may also be distributed all over the body including the face. We can detect oedema by pressing the skin of the leg with your fingers. Because of the accumulation of fluid under the skin, when you press there will be a depression at the place where the pressure is applied.
ii) Failure of growth: Children with kwashiorkor weigh only about 60per cent of the weight of normal children for their age. For example, a three-year-old healthy normal boy weighs about 13.5 kgs. whereas, another boy of the same age but suffering from kwashiorkor may only weigh 60 %  i.e about 8 kg. In other words, they are very much lighter than healthy normal children of their age.
iii) Irritability: The child suffering from kwashiorkor is generally irritable and has no interest in his/her surroundings.
iv) Skin Changes; The skin of the child may peel off easily leaving behind cracks or sores.
v) Hair Changes: The hair may become sparse and can be easily pulled off. The hair usually loses its black colour and appears reddish-brown.  
vi) Moon Face: The face of the child suffering from kwashiorkor may appear puffy with the cheeks sagging. This condition is normally known as a moon face.    
vii) Associated deficiencies: The children may have signs of other deficiencies like those of vitamin A and B-complex deficiencies.      
viii) Associated diseases: The child is often suffering from watery diarrhoea (frequent loose motions) or severe respiratory infection (cough). The children may be suffering from measles, a childhood disease.

Q  Xerophthalmia     2
Q  Briefly describe the clinical features of xerophthalmia.   5
Q  Causative factors of Xerophthalmia                            4
A  Xerophthalmia refers to the eye manifestations (signs) because of vitamin A deficiency. Blindness as a result of xerophthalmia is an important public health problem in India.

Clinical features of xerophthalmia. -
a)  Night Blindness: One of the earliest manifestations of xerophthalmia is night blindness. Individuals suffering from night blindness cannot see in dim light or around dusk. The child will be unable to see even the meal plate kept in front of him/her in dim light.
b)  Conjunctival Xerosis: Xerosis means dryness. In the normal eyes, the membrane covering the white portion of the eye (i.e.conjunctiva) is bright, white, and moist. In the case of xerophthalmia, it becomes discolored (muddy coloured), dry, and loses its brightness. This is known as conjunctival xerosis.
C  Bitot spots: In addition to xerosis, dry foamy, triangular spots may appear on the conjunctiva. These are known as Bitot's spots. If they are neglected, the changes may continue to progress affecting the cornea of the eye and may lead to irreversible blindness.
d)  Corneal xerosis:  When the deficiency of vitamin A becomes severe, the cornea becomes dry and dull and appears like ground glass. This condition is called corneal xerosis which means dryness of the cornea. This condition should be treated as an emergency. If it is not treated immediately with vitamin A, the child can develop ulcers in the cornea. Corneal ulcers when healed leave white scars known as leucoma that interferes with normal vision.  
e)  keratomalacia: The most dangerous form of xerophthalmia is known as keratomalacia. In this condition, the cornea becomes very soft and raw and easily infected. It leads to the destruction of the eye. In other words, the eye gets completely melted and destroyed. This condition leads to irreversible blindness.  

The causative factors of Xerophthalmia -
a) Dietary inadequacy of vitamin A: The primary cause of xerophthalmia is the deficiency of vitamin A in our diet. In the villages and urban slums, among the low-income groups, the intake of vitamin A is less than a quarter of the Recommended Dietary Intakes (RDI).

b)  Maternal Malnutrition: Indian children from very poor rural families are born with low stores of vitamin A in the liver it is because their mothers are also deficient in vitamin A. Due to inadequate consumption of vitamin A, the child develops xerophthalmia.  
c)  Infections and Infestations: Diarrhoea and respiratory infections and worm infestations like roundworm disease are very common in children. These are known to decrease the absorption of vitamin A and lead to deficiency. Measles, one of the childhood infections, is another important cause of xerophthalmia.    

Q  Clinical features of Vitamin A deficiency                6
A   Above
Q  How to prevent Vitamin A deficiency?
A  Consume Vitamin A rich diet: the most rational method of prevention of vitamin A deficiency is to make sure that communities consume foods rich in vitamin A regularly. Inexpensive foods like green leafy vegetables (palak, amaranth, etc.), yellow vegetables (yellow pumpkin and carrots) and fruits (papaya and mango) are good sources of beta carotene.
Periodic administration of Vitamin A: It is possible to build up sufficient vitamin A stores in a child by giving large doses of vitamin A periodically. Under the program, the children between the ages of one and five years are given a massive oral dose of vitamin A (200.000 IU) once every six months. The distribution of vitamin A is carried out by the village level health workers like health workers of the State Governments.  

Q  Explain the causative factors and preventive measures for anaemia.   8
Q  Preventive measures of Iron deficiency                  5
Q  Discuss in detail how nutritional anemia can be prevented.  7
A  Causes - Anaemia occurs due to iron deficiency or folic acid and vitamin B12 deficiency. The various causes of iron deficiency anaemia are -dietary deficits or less absorption of iron and loss of iron from the body.
a) Dietary inadequacy: The deficiency of iron in the body can be due to two reasons - low dietary intake of iron or reduced (low) absorption of iron in the body. The iron requirement is high in the body in certain physiological conditions especially in infants, children & women in reproductive years(as a result of menstruation, pregnancy & lactation). If iron intake during these periods is not adequate, it may result in anaemia. Iron absorption problem
b) Losses of Iron: The second major cause of anaemia is increased loss of iron from the body. In adult women of reproductive age, loss of iron occurs due to menstrual loss, loss of iron occurs during pregnancy, delivery, and lactation. If proper care of women is not taken during these periods, it can lead to anaemia. Iron losses from the body are also more in the case of people suffering from hookworm and other worm infestations. Heavy loss of iron from the body in conditions of surgery or accident can also lead to anaemia.
Folic acid and Vitamin B12 deficiency: Anaemia can also occur due to the deficiency of folic acid and vitamin B12 as they play a major role in blood formation. People who are strict vegetarians but avoid green leafy vegetables or eat no animal products are prone to it.  

Preventive measures for anaemia -  
a) Dietary measures: The most rational method of prevention of anaemia is to ensure the consumption of diets by the population that is rich in iron. The women should be particularly encouraged to consume iron-rich foods regularly. Inexpensive sources of iron are green leafy $vegetables (palak, amaranth, etc), whole wheat flour, rice flakes, other vegetables like (lotus stem), groundnuts, apple, jaggery, amla. These foods should be consumed as they are rich sources of iron, care should be taken that enough vitamin C-rich and protein-rich foods are consumed along with them (as they enhance absorption of iron).  
b) Fortification of foods: Certain food items that are consumed on a regular basis are fortified with iron to improve the iron content in them and subsequently increased consumption of iron by vulnerable sections of the population. Baby foods are fortified with iron to protect infants from anaemia, today many food items are fortified with iron like biscuits, wheat flour.
c) Distribution of iron and folic acid tablets: By consuming iron tablets, the hemoglobin levels in the blood can be raised. For over the last 20 years, iron (60 mg) and folic acid (500pg) tablets are distributed among the vulnerable sections of the community (those who are more prone to deficiency disorders) women, pregnant and lactating women, and children (1-5 years).

Q  Prevention and control of IDD     5
Q  Give any two clinical features of Iodine deficiency disorder.    2
Q  Spectrum of iodine deficiency disorders   5
Q  Give the clinical manifestations of iodine deficiency disorder. 4
A  Causes - In mountainous and hilly regions, iodine deficiency occurs because of the washing down of the soil from iodine content due to heavy rains and glaciers. In the case of plains, repeated floods deplete the iodine content in soil and water. As a result, all animal and vegetable foods dependent on the soil and water are deficient in iodine. Thus, when these foods which are deficient in iodine are consumed, it leads to iodine deficiency.
Apart from this, certain chemical substances called goitrogens (goiter producing substances) interfere with the utilization of iodine by the thyroid gland. Foods like cabbage and radish are contained goitrogens. Consumption of these foods in large quantities in some cases may lead to iodine deficiency.    
 Two clinical features of Iodine deficiency disorder - Goitre and cretinism
The clinical manifestations of both goitre and cretinism are -
Goitre - Iodine is essential for the normal functioning of an endocrine gland known as the thyroid gland. The thyroid gland secretes a hormone called thyroxine, which is very important for normal human development and health. Iodine helps in the formation of thyroxine. When iodine is inadequate, the thyroid gland enlarges in an attempt to produce thyroxine for the body's needs. Due to the deficiency of iodine in the body, the thyroid gland enlarges in order to trap more iodine (whatever is available). The swelling or enlargement can vary in size depending on the severity of the goitre. The word goitre means swelling/or enlargement of the thyroid gland.
Cretinism: It is the most severe manifestation of IDD. Cretinism refers to the adverse effects of iodine deficiency on the infant and young child. Iodine deficiency interferes with the brain development of the foetus. This means it can cause irreversible brain damage even before birth. If an infant is born to an iodine-deficient mother, he or she is likely to suffer from hypothyroidism. If this condition of iodine deficiency or hypothyroidism continues further even after the birth of the child, the child may suffer from a series of disorders which may include mental retardation, growth failure, speech and hearing defects, neuromuscular disorders, paralysis.

Prevention and Control - Control: Since IDD is due to reduced intake of iodine, the rational method is to ensure a sufficient intake of iodine by the population living in areas where IDD is common. A few methods to increase the iodine intake of people residing in endemic regions include:
1) Use of Iodized salt: The oldest and the most extensively used method is fortification (enrichment) of common salt with iodine (Potassium iodate). For 10 g of common salt about 150ug iodine is added. The iodized salt (common salt to which iodine is added) smells, tastes and even looks exactly like the common salt.
2) Use of tablets of sodium or potassium iodide: The intake of sodium/potassium iodate tablets to school children in areas where goitre and cretinism are severe. The addition of iodine to the drinking water supply has been tried in some countries.    
3) Use of Iodized oil: During the last decade, injection of oil, to which iodine has been added is given in areas where goitre and cretinism is severe. The advantage is that an injection of a 1 ml dose of iodized oil can provide protection to an individual for 3-5 years.   

ANC - 1

10th Part

a)A male child of one year weighs 4.7 kg as against the normal of 9.5 kg. The child is suffering from ......... form of PEM.
Severe (i.e.4.7*100/ 9.5 = 49.5% which is less than 50% of the normal weight for age.) 

b) A child who has extensive wasting of muscle is suffering from ........
marasmus

c) In the case of PEM, subclinical forms can be identified by using.
body-weight

d) ........................is the condition characterized by sagging cheeks and puffy face.
A moon face

e) .....................................is. the condition, where external medical examination may not show any sign of the disease. 
A  subclinical forms

Q  List 3 measures which you would like to adopt to prevent PEM in a village community.
 a) Improve maternal nutrition by ensuring adequate intake of energy-rich foods by pregnant women to increase the birth weight of their offsprings.
b) Breastfeed the child as long as possible.
c) Introducing supplementary food in addition to breast milk by the age of 6 months.
d) Children should be fed 5-6 times a day.
e) Prompt treatment of minor ailments like diarrhoea and respiratory infection.
f) Immunization of children against diseases.

Q  List the main causes of PEM in infants.
Poverty, Maternal malnutrition, Infections, and poor hygiene. Ignorance, Wrong child feeding practices.  

a) Xerophthalmia is due to the deficiency of. .........................in the diet. 
 vitamin A
b   Conjunctival xerosis means ................... of the conjunctiva.   
A  dryness 

c) The most dangerous consequence of xerophthalmia is irreversible....…
 blindness 

d) Dry, foamy, triangular spots appearing on the conjunctiva are called.. .....…
 bitot spots

Q  The clinical features of xerophthalmia relating to the cornea are: 
  Corneal xerosis, corneal ulceration, and keratomalacia.

Q  List the main causes of xerophthalmia in India.
a) Maternal malnutrition
b) Deficiency of vitamin A in the diets
c) Infections like diarrhoea, measles, and. respiratory infections
d) Infestations like roundworm disease
e) Ignorance leading to avoidance of vitamin A-rich foods  

Q  What advice will you give to a mother of a preschool child in a village to prevent xerophthalmia?  
# Give daily one of the inexpensive local foods like green leafy vegetables, carrots, yellow pumpkin, papaya, or mango.
# Provide a massive oral dose of Vitamin A (200,000 IU) once every six months.  

Q  List the population groups at risk of developing anemia.
 Pregnant women, lactating women, children under the age of five years, and women in the reproductive age group.   

Fill in the blanks :
a) Ninety-five percent of anemia in India is due to. ..................deficiency.
 Iron
b) Anaemia arises when the transport of ...................by the blood is insufficient to meet the needs of the body. 
 Oxygen  

c) In pregnant women, the hemoglobin level below ...................in the blood is considered as anaemia.
 A   11 g per 100ml

d) Milk is a ...................source of iron. 
poor

Match the following :
a) Intrinsic factor '                  i)  B12
b) Absorption of iron             ii) Animal foods
c) Common salt                     iii) Fortification
d) Iron                                    iv) Folic acid  

Q  Which are the areas in India where iodine deficiency has been prevalent for years 
A   Sub Himalayan belt extending from Jammu & Kashmir in the north to Nagaland in east   

Q  List the methods of control of iodine deficiency disorders.
Iodization of salt is the simplest method. In remote areas intramuscular injections of iodized oil can protect the community for 3-5 years against IDD or sodium/potassium iodide tablet can also be given.

Q  Fill in the blanks :
a) Iodine is required for the formation of .................hormone. 
 thyroxine 
b) We require ....................ug of iodine per day. 
 150
c) Substances which interfere with the utilization of iodine by the thyroid gland are called..  ......................…
  goitrogens
d) The most suitable method for control of iodine deficiency in India is the use of. .......
  (iodized salt)

e) ..........................and ...........................are the most easily recognized forms of IDD.
  Goitre, cretinism